Latest Publication

Measuring DNA quality by dPCR using probability statistics

Here we discuss a method to fexibly analyze DNA quality using digital PCR. It can also be used to quantify linkage of sequences in a single DNA sequence. The method is based on quantifying linkage of different sequences along a long DNA sequence. It is flexible towards using multiple assays per DNA sequence, to get a detailed idea of the level of DNA shearing and it works on a diverse range of DNA concentrations. A shiny app is available to analyze your own data.

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Featured Publications

Review - Digital PCR Partition Classification

ummary of all available digital PCR partition classification approaches and the challenges

The Digital MIQE Guidelines Update

Minimum Information for Publication of Quantitative Digital PCR Experiments for 2020

Partition classification: ddpcRquant

Threshold determination for single channel droplet digital PCR experiments.

Flexible data-analysis using GLMM

Flexible analysis of digital PCR experiments using generalised linear mixed models.

Key Publications from DIGPCR

2018, Analytical and Bioanalytical Chemistry
On determining the power of digital PCR experiments
2017, Analytical and Bioanalytical Chemistry
Quality control of digital PCR assays and platforms